5-Amino-2-Methoxy-Isonicotinic Acid

5-Amino-2-Methoxy-Isonicotinic Acid - Names and Identifiers

Name	5-Amino-2-methoxy-4-pyridinecarboxylic acid
Synonyms	5-AMINO-2-METHOXY-ISONICOTINIC ACID 5-Amino-2-Methoxy-Isonicotinic Acid 5-amino-2-methoxypyridine-4-carboxylicaci 5-Amino-2-methoxy-4-pyridinecarboxylic acid 5-AMINO-2-METHOXYPYRIDINE-4-CARBOXYLIC ACID 5-Amino-2-methoxypyridine-4-carboxylic acid 4-Pyridinecarboxylic acid, 5-amino-2-methoxy-
CAS	183741-91-5
InChI	InChI=1/C7H8N2O3/c1-12-6-2-4(7(10)11)5(8)3-9-6/h2-3H,8H2,1H3,(H,10,11)

5-Amino-2-Methoxy-Isonicotinic Acid - Physico-chemical Properties

Molecular Formula	C7H8N2O3
Molar Mass	168.15
Density	1.384
Melting Point	217-221℃
Boling Point	469.5°C at 760 mmHg
Flash Point	237.7°C
Vapor Presure	1.29E-09mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.611

5-Amino-2-Methoxy-Isonicotinic Acid - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
HS Code	29339900

5-Amino-2-Methoxy-Isonicotinic Acid - Introduction

acid is an organic compound whose properties are as follows:

Nature:
-Appearance: Colorless to pale yellow crystalline solid
-Melting point: About 210 ℃
-Solubility: Soluble in water and some organic solvents, such as ethanol and dimethyl sulfoxide

Use:
-acid is often used as an intermediate in organic synthesis and can be used to synthesize other compounds or drugs
-It can also be used as a ligand for metal ions, used for coordination chemical reactions and catalytic reactions

Method:
-the acid is usually made by the following steps:
1. Methoxylation of pyridine by methanol to obtain 2-methoxypyridine
2. React 2-methoxypyridine with bromomethanesulfonic acid to obtain 2-methoxypyridine -4-methanesulfonic acid
3. Reacting 2-methoxypyridine-4-methanesulfonic acid with ammonia to obtain 5-amino-2-methoxypyridine-4-methanesulfonic acid
4. Finally, neutralize the reaction with an alkaline solution to obtain acid.

Safety Information:
-the acid is generally safer under normal conditions of use.
-As an organic compound, it may be irritating to the skin, eyes and respiratory tract.
-Wear appropriate protective equipment such as gloves, goggles and masks during use.
-Avoid contact with oxidants and strong acids during storage and handling.
-If taken by mistake or inhaled by mistake, seek medical attention immediately. In case of skin or eye contact, rinse with plenty of water and seek medical attention if necessary.

Last Update：2024-04-09 21:00:56